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How late is too late for PrEP?

You can take PrEP 3 hours late and still be protected against HIV. PrEP starts to lose its effectiveness after 24 hours, with those who miss a pill every day for a week after a month of taking it on schedule going down to 90% effectiveness.
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When is it too late to take PrEP?

Both the drugs in PrEP stay in your body to allow for a few hours being late with dosing. It is better to try to take them at the right time. The after sex doses with on demand dosing only need to be taken 24 hours and 48 hours after the first double dose.
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What happens if you forget to take PrEP after 5 hours?

If you are taking PrEP pills: Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose of PrEP pills to make up for a missed one.
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Is PrEP effective after 3 days?

No. With proper medical guidance, people can safely start and stop taking PrEP at different points in their lives. However, any time you start PrEP, it is important to remember that it generally takes at least 7-22 days of daily use for it to reach full effectiveness.
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Can I stop PrEP after 30 days?

It's important to continue taking PrEP for at least awhile after your last potential HIV exposure. The safest course of action would be to continue taking PrEP for at least 28 days after your last exposure. There is no information regarding less than 28 days of dosing after vaginal sex.
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#AskTheHIVDoc: Is it too late to start HIV treatment?

Can I take PrEP for 28 days?

Generally speaking, cis-gender men taking on-demand PrEP should continue taking the PrEP medication for at least 2 days after any possible exposure. Anyone taking daily PrEP should continue taking the medication for 28 days after the last possible exposure.
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Is PrEP effective after 20 days?

For receptive vaginal sex and injection drug use, PrEP pills reach maximum protection at about 21 days of daily use.
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Does PrEP work for tops?

Yes. PrEP 2-1-1 was studied in people who had insertive anal sex (who were the “top”). PrEP 2-1-1 is as effective for tops as it is for bottoms when having anal sex.
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Is 2 days of PrEP enough?

For vaginal/frontal sex, you must at the very least have taken PrEP for 6 days a week to have good protection. If you miss more than 1 dose a week, you are not going to be protected against HIV if you are having condomless sex.
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Can I stop PrEP after 7 days?

Can I stop PrEP completely? You can stop taking PrEP whenever you feel it is no longer necessary for you. However, remember to continue taking PrEP daily for seven days if you've recently had receptive vaginal sex or continue taking PrEP daily for two days if you've recently given or received anal sex.
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What to avoid when taking PrEP?

If you are using HIV PrEP do not take non-steroidal anti-inflammatory drugs (NSAIDs) such as:
  • ibuprofen.
  • diclofenac.
  • naproxen.
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What happens if you take 2 PrEP pills in one day?

Taking two PrEP pills at once or on the same day is not harmful. In fact, taking two pills together is the recommended way to start using PrEP in some cases. If you accidentally take two PrEP pills in one day, there is no need for concern. Simply continue taking your PrEP as advised the following day.
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How many days can you skip PrEP and still be protected?

Missing two days of PrEP is not recommended, but you will still likely have some protection against HIV. Take your next dose as planned, and talk to your healthcare practitioner if you have trouble sticking to a daily PrEP schedule.
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How often does PrEP fail?

When people take PrEP as it's prescribed, it is extremely effective. Fewer than 20 breakthrough cases have been reported in scientific journals, out of about one million people taking PrEP worldwide. The highest risk factor of acquiring HIV while taking PrEP is poor adherence.
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Is it OK to take PrEP before bed?

Take PrEP every day

You can take PrEP any time during the day, with or without food. PrEP works best if you take it at the same time every day. You may want to take PrEP before or after a daily activity, like when you eat breakfast, or when you brush your teeth before bed.
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Can PrEP cause false positive?

Most people prescribed PrEP who acquire HIV infection will do so due to medication nonadherence [7–9], and the vast majority of anomalous HIV test results in persons adherent to PrEP will be false-positive.
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Am I safe if my partner is on PrEP?

If your partner is on PrEP, they are protecting themselves from HIV, which helps protect you. As a result, it is extremely unlikely that you would ever get HIV from a person on PrEP, because that person is almost certainly not living with HIV.
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What does PrEP do to your body?

The drug works by preventing HIV from replicating in the body. PrEP acts as a catalyst that helps the body produce antibodies, which help diseases causing germs and viruses. After contact with the virus, the tenofovir and emtricitabine block the enzyme needed by the virus to replicate.
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What are the negative side effects of PrEP?

PrEP is safe, but some people experience side effects like diarrhea, nausea, headache, fatigue, and stomach pain. These side effects usually go away over time. Tell your health care provider about any side effects that are severe or do not go away. Learn more about side effects from Truvada®, Descovy®, and Apretude.
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Can PrEP change body shape?

Preexposure prophylaxis (PrEP) with tenofovir disoproxil fumarate /emtricitabine (TDF/FTC) leads to small losses of body fat but does not appear to affect fat distribution or lean body mass.
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Is PrEP 90% effective?

When used daily, PrEP has a low failure rate. The effectiveness of PrEP can range from 44% to 92% depending on adherence. The effectiveness of PrEP is 44% when it is taken imperfectly. The effectiveness of PrEP is 92% when it is taken every day.
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How can you tell if someone is on PrEP?

How do I know if someone I'm having sex with is really on PrEP? Only you can be sure if you are using PrEP to prevent HIV transmission. If you are not sure your sexual partner is on PrEP (or adhering to PrEP correctly), condoms and water based lube is recommended.
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Can I get pregnant while using PrEP?

PrEP and fertility

There is no evidence to suggest that taking PrEP reduces fertility in either men or women.
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Can I infect someone while on PEP?

If taken within 72 hours after possible exposure, PEP is highly effective in preventing HIV. But to be safe, you should take other actions to protect your partners while you are taking PEP. This includes always using condoms with sexual partners and not sharing needles, syringes, or other equipment to inject drugs.
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What is the success rate of PrEP?

If you take your PrEP pills as directed, they work quite well against future HIV transmission. You should be able to protect yourself from HIV infection from sexual contact 99% of the time. If you inject drugs and share needles, PrEP isn't as effective but can protect you in 74% of HIV exposures.
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