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How many days can you skip PrEP and still be protected?

If you miss one or two pills occasionally, this will be fine on a daily dosing regime. If you are daily dosing and miss more than a week of pills you will need to wait until you've had at least seven daily doses of PrEP or take a two-pill dose before you are completely protected from contracting HIV again.
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What happens if I miss 3 days of PrEP?

An occasional missed dose of PrEP pills will not greatly impact overall effectiveness, but it is important to take the medicine as prescribed. If you miss doses frequently, talk to your health care provider.
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How long after stopping PrEP am I protected?

Key takeaways. There isn't definitive data to confirm how long you are protected after stopping PrEP. While there is likely increased protection for up to a week after stopping PrEP, this protection won't be as high during a normal course of PrEP. When taken correctly, PrEP offers a 99% reduction in HIV risk.
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What happens if you take 2 PrEP pills in one day?

Taking two PrEP pills at once or on the same day is not harmful. In fact, taking two pills together is the recommended way to start using PrEP in some cases. If you accidentally take two PrEP pills in one day, there is no need for concern. Simply continue taking your PrEP as advised the following day.
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Is PrEP effective after 3 days?

No. With proper medical guidance, people can safely start and stop taking PrEP at different points in their lives. However, any time you start PrEP, it is important to remember that it generally takes at least 7-22 days of daily use for it to reach full effectiveness.
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How long do I take PrEP before I'm protected?

What happens if you miss 2 days of PrEP?

Ideally, you should take PrEP daily to ensure maximum protection against HIV. However, missing one or two days of PrEP may not immediately affect protection against the virus. PrEP has a reasonably long half-life, so it remains in the body long enough to have some protective effect even after missing a dose.
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Is 2 days of PrEP enough?

For vaginal/frontal sex, you must at the very least have taken PrEP for 6 days a week to have good protection. If you miss more than 1 dose a week, you are not going to be protected against HIV if you are having condomless sex.
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Does PrEP work for tops?

Yes. PrEP 2-1-1 was studied in people who had insertive anal sex (who were the “top”). PrEP 2-1-1 is as effective for tops as it is for bottoms when having anal sex.
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How many days of PrEP can I miss?

If you are taking daily PrEP, then do not worry if you sometimes miss one or two pills. Everyone taking daily PrEP will get good protection so long as you take at least four pills every week.
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What to avoid when taking PrEP?

If you are using HIV PrEP do not take non-steroidal anti-inflammatory drugs (NSAIDs) such as:
  • ibuprofen.
  • diclofenac.
  • naproxen.
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How much protection after 3 days of PrEP?

According to levels of drug detected in peripheral blood mononuclear cells (PBMCs), and comparisons of those results to drug levels estimated in previous research to correspond to varying degrees of protection against HIV, one day on PrEP led to a 75 to 91 risk reduction, three days meant a 95 to 97 percent risk ...
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How long is Truvada effective after stopping?

Truvada stays in your system for about a week after you stop taking it. The main ingredient in Truvada, the HIV prophylaxis drug, typically has a half-life of more than six days, according to a study published in the Journal of Antimicrobial Chemotherapy.
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What happens if you stop taking PrEP for a few days?

In most cases, stopping PrEP won't cause any immediate side effects — but it may raise your risk of HIV, especially if you have risk factors that increase your chances of HIV exposure.
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Does it matter if I miss a day of PrEP?

If you take PrEP every day and miss your dose, you can still take it as long as it's within 12 hours of when you were supposed to take it. If it's longer than 12 hours, you'll have to miss that dose and take the next one at the usual time. It's important not to miss your dose but if that does happen, it's OK.
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Does PrEP have to be exactly 24 hours?

Taking PrEP

taken regularly (one tablet per day). only taken when needed (two tablets two to 24 hours before sex, one tablet 24 hours later and a further tablet 48 hours after that).
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How often does PrEP fail?

When people take PrEP as it's prescribed, it is extremely effective. Fewer than 20 breakthrough cases have been reported in scientific journals, out of about one million people taking PrEP worldwide. The highest risk factor of acquiring HIV while taking PrEP is poor adherence.
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What happens if you miss 2 days of PEP?

Do not double a dose if you miss one. If you do miss a dose and you remember in less than 24 hours, take the next one as soon as you remember. If you miss more than 48 hours of PEP it will be discontinued.
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What happens if I don't take PrEP for a week?

If you miss one or two pills occasionally, this will be fine on a daily dosing regime. If you are daily dosing and miss more than a week of pills you will need to wait until you've had at least seven daily doses of PrEP or take a two-pill dose before you are completely protected from contracting HIV again.
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How many doses of Truvada can you miss?

Dr. Demetre: So now that you're on PrEP, if you miss 1 or 2 doses it's not a big deal. If you make a habit of it, if you're missing 3 or 4 doses a week, it is a big deal. The more you take it on schedule, the more likely it works.
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Is it better to take PrEP at night or morning?

Take PrEP every day

You can take PrEP any time during the day, with or without food. PrEP works best if you take it at the same time every day. You may want to take PrEP before or after a daily activity, like when you eat breakfast, or when you brush your teeth before bed.
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How can you tell if someone is on PrEP?

How do I know if someone I'm having sex with is really on PrEP? Only you can be sure if you are using PrEP to prevent HIV transmission. If you are not sure your sexual partner is on PrEP (or adhering to PrEP correctly), condoms and water based lube is recommended.
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What is the most discreet way to get PrEP?

If you do not see any clinics near you or ones that you are comfortable going to, you may be able to get PrEP delivered discreetly to your home or by going to a pharmacy. Options include: Tele-PrEP (including NURX and PlushCare) Walgreens Healthcare Clinics, CVS minute clinics, or other pharmacies.
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Am I safe if my partner is on PrEP?

If your partner is on PrEP, they are protecting themselves from HIV, which helps protect you. As a result, it is extremely unlikely that you would ever get HIV from a person on PrEP, because that person is almost certainly not living with HIV.
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What does PrEP do to your body?

The drug works by preventing HIV from replicating in the body. PrEP acts as a catalyst that helps the body produce antibodies, which help diseases causing germs and viruses. After contact with the virus, the tenofovir and emtricitabine block the enzyme needed by the virus to replicate.
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How late is too late for PrEP?

You can take PrEP 3 hours late and still be protected against HIV. PrEP starts to lose its effectiveness after 24 hours, with those who miss a pill every day for a week after a month of taking it on schedule going down to 90% effectiveness.
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